Sex-related differences in carotid plaque features and inflammation
نویسندگان
چکیده
منابع مشابه
Sex differences in carotid plaque and stenosis.
BACKGROUND AND PURPOSE Women are relatively protected from cardiovascular events; they are 3 times as likely as men to survive to age 90 years. Although clinical trials show an excess of thrombotic events with estrogen/progestin hormone replacement therapy, much experimental and epidemiological evidence suggests that estrogen may have beneficial effects on endothelial function and atheroscleros...
متن کاملSex differences in carotid bifurcation anatomy and the distribution of atherosclerotic plaque.
BACKGROUND AND PURPOSE Plaque formation at arterial bifurcations depends on vessel anatomy, particularly the relative sizes of the branches, and the ratio of the outflow to inflow area. The facts that carotid plaque is more common in men and that carotid bruits in the absence of stenosis are more frequent in women raise the possibility that there are sex differences in carotid bifurcation anato...
متن کاملSex differences in patients with asymptomatic carotid atherosclerotic plaque: in vivo 3.0-T magnetic resonance study.
BACKGROUND AND PURPOSE Stroke prevention with carotid endarterectomy in asymptomatic men with carotid stenosis is greater than in women. Men have a higher incidence of stroke <75 years of age. Sex differences in plaque characteristics may help explain this, because several plaque features, including a thin/ruptured fibrous cap, larger lipid-rich/necrotic core, and hemorrhage, are associated wit...
متن کاملCarotid plaque and candidate genes related to inflammation and endothelial function in Hispanics from northern Manhattan.
BACKGROUND AND PURPOSE The genetic influence on carotid atherosclerotic plaque is mostly unknown. This study examines the association between carotid plaque and single nucleotide polymorphisms in selected genes implicated in inflammation and endothelial function. METHODS A total of 43 genes (197 single nucleotide polymorphisms) involved in inflammation and endothelial function were interrogat...
متن کاملSex Differences in Sex Hormones, Carotid Atherosclerosis, and Stroke.
There are notable sex differences in cardiovascular disease. Although the cumulative incidence of cardiovascular disease in women lags behind that of men by ≈7 to 10 years, strokes comprise a larger proportion of cardiovascular events in women than in men. In terms of clinical impact, aspirin used for primary prevention is associated with a significance reduction in stroke women but not myocard...
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ژورنال
عنوان ژورنال: Journal of Vascular Surgery
سال: 2013
ISSN: 0741-5214
DOI: 10.1016/j.jvs.2012.07.052